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Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel

C-type inactivation is a time-dependent process of great physiological significance that is observed in a large class of K(+) channels. Experimental and computational studies of the pH-activated KcsA channel show that the functional C-type inactivated state, for this channel, is associated with a st...

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Detalles Bibliográficos
Autores principales: Li, Jing, Shen, Rong, Rohaim, Ahmed, Mendoza Uriarte, Ramon, Fajer, Mikolai, Perozo, Eduardo, Roux, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352720/
https://www.ncbi.nlm.nih.gov/pubmed/34357375
http://dx.doi.org/10.1085/jgp.202112875