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Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel
C-type inactivation is a time-dependent process of great physiological significance that is observed in a large class of K(+) channels. Experimental and computational studies of the pH-activated KcsA channel show that the functional C-type inactivated state, for this channel, is associated with a st...
Autores principales: | Li, Jing, Shen, Rong, Rohaim, Ahmed, Mendoza Uriarte, Ramon, Fajer, Mikolai, Perozo, Eduardo, Roux, Benoît |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352720/ https://www.ncbi.nlm.nih.gov/pubmed/34357375 http://dx.doi.org/10.1085/jgp.202112875 |
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