Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

The five-membered pyrrolidine ring is one of the nitrogen heterocycles used widely by medicinal chemists to obtain compounds for the treatment of human diseases. The great interest in this saturated scaffold is enhanced by (1) the possibility to efficiently explore the pharmacophore space due to sp(...

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Detalles Bibliográficos
Autores principales: Li Petri, Giovanna, Raimondi, Maria Valeria, Spanò, Virginia, Holl, Ralph, Barraja, Paola, Montalbano, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352847/
https://www.ncbi.nlm.nih.gov/pubmed/34373963
http://dx.doi.org/10.1007/s41061-021-00347-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352847/
https://www.ncbi.nlm.nih.gov/pubmed/34373963
http://dx.doi.org/10.1007/s41061-021-00347-5

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