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Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds
The five-membered pyrrolidine ring is one of the nitrogen heterocycles used widely by medicinal chemists to obtain compounds for the treatment of human diseases. The great interest in this saturated scaffold is enhanced by (1) the possibility to efficiently explore the pharmacophore space due to sp(...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352847/ https://www.ncbi.nlm.nih.gov/pubmed/34373963 http://dx.doi.org/10.1007/s41061-021-00347-5 |