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Early combination therapy of empagliflozin and linagliptin exerts beneficial effects on pancreatic β cells in diabetic db/db mice

Effects of combination therapy of dipeptidyl peptidase-4 (DPP-4) inhibitor and sodium-glucose co-transporter 2 (SGLT2) inhibitor on β-cells are still unclear, although combination agent of these two drugs has become common in clinical practice. Therefore, we aimed to elucidate the effects of DPP-4 i...

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Detalles Bibliográficos
Autores principales: Fushimi, Yoshiro, Obata, Atsushi, Sanada, Junpei, Nogami, Yuka, Ikeda, Tomoko, Yamasaki, Yuki, Obata, Yoshiyuki, Shimoda, Masashi, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352868/
https://www.ncbi.nlm.nih.gov/pubmed/34373487
http://dx.doi.org/10.1038/s41598-021-94896-w