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Single dose rVSVΔG-JUNVGP vaccine protects guinea pigs against lethal Junin virus challenge

Junin virus (JUNV) is a pathogen of biodefense importance due to its potential for aerosol transmission and mortality rates reaching 30%. Currently, there are no JUNV vaccines licensed by the United States Food and Drug Administration (FDA) for at-risk individuals. A vaccine based on recombinant ves...

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Detalles Bibliográficos
Autores principales: Sorvillo, Teresa E., Cross, Robert W., Johnson, Dylan M., Dobias, Natalie S., Fenton, Karla A., Mire, Chad E., Geisbert, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352877/
https://www.ncbi.nlm.nih.gov/pubmed/34373461
http://dx.doi.org/10.1038/s41541-021-00361-0