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Minimally invasive quantification of cerebral P2X7R occupancy using dynamic [(18)F]JNJ-64413739 PET and MRA-driven image derived input function
[(18)F]JNJ-64413739 has been evaluated as PET-ligand for in vivo quantification of purinergic receptor subtype 7 receptor (P2X7R) using Logan graphical analysis with a metabolite-corrected arterial plasma input function. In the context of a P2X7R PET dose occupancy study, we evaluated a minimally in...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352986/ https://www.ncbi.nlm.nih.gov/pubmed/34373571 http://dx.doi.org/10.1038/s41598-021-95715-y |