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Acrolein Induces Systemic Coagulopathy via Autophagy-dependent Secretion of von Willebrand Factor in Mice after Traumatic Brain Injury

Traumatic brain injury (TBI)-induced coagulopathy has increasingly been recognized as a significant risk factor for poor outcomes, but the pathogenesis remains poorly understood. In this study, we aimed to investigate the causal role of acrolein, a typical lipid peroxidation product, in TBI-induced...

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Detalles Bibliográficos
Autores principales: Cui, Wenxing, Wu, Xun, Feng, Dayun, Luo, Jianing, Shi, Yingwu, Guo, Wei, Liu, Haixiao, Wang, Qiang, Wang, Liang, Ge, Shunnan, Qu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353051/
https://www.ncbi.nlm.nih.gov/pubmed/33939120
http://dx.doi.org/10.1007/s12264-021-00681-0