Cargando…
Acrolein Induces Systemic Coagulopathy via Autophagy-dependent Secretion of von Willebrand Factor in Mice after Traumatic Brain Injury
Traumatic brain injury (TBI)-induced coagulopathy has increasingly been recognized as a significant risk factor for poor outcomes, but the pathogenesis remains poorly understood. In this study, we aimed to investigate the causal role of acrolein, a typical lipid peroxidation product, in TBI-induced...
Autores principales: | Cui, Wenxing, Wu, Xun, Feng, Dayun, Luo, Jianing, Shi, Yingwu, Guo, Wei, Liu, Haixiao, Wang, Qiang, Wang, Liang, Ge, Shunnan, Qu, Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353051/ https://www.ncbi.nlm.nih.gov/pubmed/33939120 http://dx.doi.org/10.1007/s12264-021-00681-0 |
Ejemplares similares
-
Death after discharge: prognostic model of 1-year mortality in traumatic brain injury patients undergoing decompressive craniectomy
por: Cui, Wenxing, et al.
Publicado: (2021) -
20‐HETE synthesis inhibition attenuates traumatic brain injury–induced mitochondrial dysfunction and neuronal apoptosis via the SIRT1/PGC‐1α pathway: A translational study
por: Cui, Wenxing, et al.
Publicado: (2020) -
Single‐Nucleus RNA Sequencing Reveals that Decorin Expression in the Amygdala Regulates Perineuronal Nets Expression and Fear Conditioning Response after Traumatic Brain Injury
por: Shi, Yingwu, et al.
Publicado: (2022) -
Acrolein Aggravates Secondary Brain Injury After Intracerebral Hemorrhage Through Drp1-Mediated Mitochondrial Oxidative Damage in Mice
por: Wu, Xun, et al.
Publicado: (2020) -
MicroRNA-124/Death-Associated Protein Kinase 1 Signaling Regulates Neuronal Apoptosis in Traumatic Brain Injury via Phosphorylating NR2B
por: Shi, Yingwu, et al.
Publicado: (2022)