PTEN Hamartoma Tumor Syndrome: Skin Manifestations and Insights Into Their Molecular Pathogenesis

Germline PTEN pathogenic variants cause a spectrum of disorders collectively labeled PTEN Hamartoma Tumor Syndrome (PHTS) and featured by hamartomas, developmental anomalies and increased cancer risk. Studies on experimental models provided evidence that PTEN is a “haploinsufficient” tumor-suppresso...

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Detalles Bibliográficos
Autores principales: Innella, Giovanni, Bonora, Elena, Neri, Iria, Virdi, Annalucia, Guglielmo, Alba, Pradella, Laura Maria, Ceccarelli, Claudio, Amato, Laura Benedetta, Lanzoni, Anna, Miccoli, Sara, Gasparre, Giuseppe, Zuntini, Roberta, Turchetti, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353102/
https://www.ncbi.nlm.nih.gov/pubmed/34386506
http://dx.doi.org/10.3389/fmed.2021.688105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353102/
https://www.ncbi.nlm.nih.gov/pubmed/34386506
http://dx.doi.org/10.3389/fmed.2021.688105

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