The functional GRHL3-filaggrin axis maintains a tumor differentiation potential and influences drug sensitivity

Current therapies for treating heterogeneous cancers such as head and neck squamous cell carcinoma (HNSCC) are non-selective and are administered independent of response biomarkers. Therapy resistance subsequently emerges, resulting in increased cellular proliferation that is associated with loss of...

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Detalles Bibliográficos
Autores principales: Bai, Yuchen, Zhao, Zixuan, Boath, Jarryd, van Denderen, Bryce J., Darido, Charbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353142/
https://www.ncbi.nlm.nih.gov/pubmed/33775911
http://dx.doi.org/10.1016/j.ymthe.2021.03.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353142/
https://www.ncbi.nlm.nih.gov/pubmed/33775911
http://dx.doi.org/10.1016/j.ymthe.2021.03.016

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