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The functional GRHL3-filaggrin axis maintains a tumor differentiation potential and influences drug sensitivity
Current therapies for treating heterogeneous cancers such as head and neck squamous cell carcinoma (HNSCC) are non-selective and are administered independent of response biomarkers. Therapy resistance subsequently emerges, resulting in increased cellular proliferation that is associated with loss of...
Autores principales: | Bai, Yuchen, Zhao, Zixuan, Boath, Jarryd, van Denderen, Bryce J., Darido, Charbel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353142/ https://www.ncbi.nlm.nih.gov/pubmed/33775911 http://dx.doi.org/10.1016/j.ymthe.2021.03.016 |
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