Assessment of Lentiviral Vector Mediated CFTR Correction in Mice Using an Improved Rapid in vivo Nasal Potential Difference Measurement Protocol

Cystic Fibrosis (CF) is caused by a defect in the CF transmembrane conductance regulator (CFTR) gene responsible for epithelial ion transport. Nasal potential difference (PD) measurement is a well established diagnostic technique for assessing the efficacy of therapies in CF patients and animal mode...

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Detalles Bibliográficos
Autores principales: Cmielewski, P., Delhove, J., Donnelley, M., Parsons, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353152/
https://www.ncbi.nlm.nih.gov/pubmed/34385926
http://dx.doi.org/10.3389/fphar.2021.714452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353152/
https://www.ncbi.nlm.nih.gov/pubmed/34385926
http://dx.doi.org/10.3389/fphar.2021.714452

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