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Gene-Edited Interleukin CAR-T Cells Therapy in the Treatment of Malignancies: Present and Future

In recent years, chimeric antigen receptor T cells (CAR-T cells) have been faced with the problems of weak proliferation and poor persistence in the treatment of some malignancies. Researchers have been trying to perfect the function of CAR-T by genetically modifying its structure. In addition to th...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengchao, Miao, Lele, Ren, Zhijian, Tang, Futian, Li, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353254/
https://www.ncbi.nlm.nih.gov/pubmed/34386015
http://dx.doi.org/10.3389/fimmu.2021.718686