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Genetically Determined Chronic Low-Grade Inflammation and Hundreds of Health Outcomes in the UK Biobank and the FinnGen Population: A Phenome-Wide Mendelian Randomization Study

BACKGROUND: C-reactive protein (CRP) has been used as a biomarker of chronic low-grade inflammation in observational studies. We aimed to determine whether genetically determined CRP was associated with hundreds of human phenotypes to guide anti-inflammatory interventions. METHODS: We used individua...

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Detalles Bibliográficos
Autores principales: Si, Shucheng, Li, Jiqing, Tewara, Marlvin Anemey, Xue, Fuzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353321/
https://www.ncbi.nlm.nih.gov/pubmed/34386016
http://dx.doi.org/10.3389/fimmu.2021.720876