Bazedoxifene inhibits sustained STAT3 activation and increases survival in GBM

An important factor correlated with poor survival in glioblastoma (GBM) is the aberrant and persistent activation of STAT3, a critical transcription factor that regulates multiple genes with key roles in cell survival, proliferation, resistance to chemotherapy, and stem cell maintenance. The Interle...

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Detalles Bibliográficos
Autores principales: Wightman, Samantha M., Alban, Tyler J., Chen, Xing, Lathia, Justin D., Wang, Yuxin, Stark, George R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353354/
https://www.ncbi.nlm.nih.gov/pubmed/34365219
http://dx.doi.org/10.1016/j.tranon.2021.101192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353354/
https://www.ncbi.nlm.nih.gov/pubmed/34365219
http://dx.doi.org/10.1016/j.tranon.2021.101192

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