PARP1 deficiency protects against hyperglycemia-induced neointimal hyperplasia by upregulating TFPI2 activity in diabetic mice

Diabetes mellitus (DM) promotes neointimal hyperplasia, characterized by dysregulated proliferation and accumulation of vascular smooth muscle cells (VSMCs), leading to occlusive disorders, such as atherosclerosis and stenosis. Poly (ADP-ribose) polymerase 1 (PARP1), reported as a crucial mediator i...

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Detalles Bibliográficos
Autores principales: Wang, Zhao-yang, Guo, Meng-qi, Cui, Qing-ke, Yuan, Haitao, Shan-ji Fu, Liu, Bin, Xie, Fei, Qiao, Wen, Cheng, Jie, Wang, Ying, Zhang, Ming-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353360/
https://www.ncbi.nlm.nih.gov/pubmed/34364219
http://dx.doi.org/10.1016/j.redox.2021.102084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353360/
https://www.ncbi.nlm.nih.gov/pubmed/34364219
http://dx.doi.org/10.1016/j.redox.2021.102084

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