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PARP1 deficiency protects against hyperglycemia-induced neointimal hyperplasia by upregulating TFPI2 activity in diabetic mice
Diabetes mellitus (DM) promotes neointimal hyperplasia, characterized by dysregulated proliferation and accumulation of vascular smooth muscle cells (VSMCs), leading to occlusive disorders, such as atherosclerosis and stenosis. Poly (ADP-ribose) polymerase 1 (PARP1), reported as a crucial mediator i...
Autores principales: | Wang, Zhao-yang, Guo, Meng-qi, Cui, Qing-ke, Yuan, Haitao, Shan-ji Fu, Liu, Bin, Xie, Fei, Qiao, Wen, Cheng, Jie, Wang, Ying, Zhang, Ming-xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353360/ https://www.ncbi.nlm.nih.gov/pubmed/34364219 http://dx.doi.org/10.1016/j.redox.2021.102084 |
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