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Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice
Increasing evidence indicates the involvement of myocardial oxidative injury and mitochondrial dysfunction in the pathophysiology of heart failure (HF). Alpha-ketoglutarate (AKG) is an intermediate metabolite of the tricarboxylic acid (TCA) cycle that participates in different cellular metabolic and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353361/ https://www.ncbi.nlm.nih.gov/pubmed/34364218 http://dx.doi.org/10.1016/j.redox.2021.102088 |