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Polyfunctional KLRG-1(+)CD57(+) Senescent CD4(+) T Cells Infiltrate Tumors and Are Expanded in Peripheral Blood From Breast Cancer Patients

Senescent T cells have been described during aging, chronic infections, and cancer; however, a comprehensive study of the phenotype, function, and transcriptional program of this T cell population in breast cancer (BC) patients is missing. Compared to healthy donors (HDs), BC patients exhibit an acc...

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Detalles Bibliográficos
Autores principales: Ramello, Maria C., Núñez, Nicolás G., Tosello Boari, Jimena, Bossio, Sabrina N., Canale, Fernando P., Abrate, Carolina, Ponce, Nicolas, Del Castillo, Andrés, Ledesma, Marta, Viel, Sophie, Richer, Wilfrid, Sedlik, Christine, Tiraboschi, Carolina, Muñoz, Marcos, Compagno, Daniel, Gruppi, Adriana, Acosta Rodríguez, Eva V., Piaggio, Eliane, Montes, Carolina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353459/
https://www.ncbi.nlm.nih.gov/pubmed/34386013
http://dx.doi.org/10.3389/fimmu.2021.713132