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Quantitative analysis of m(6)A RNA modification by LC-MS

N(6)-adenosine methylation (m(6)A) of messenger RNA (mRNA) plays key regulatory roles in gene expression. Accurate measurement of m(6)A levels is thus critical to understand its dynamic changes in various biological settings. Here, we provide a protocol to quantitate the levels of adenosine and m(6)...

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Detalles Bibliográficos
Autores principales: Mathur, Lavina, Jung, Sunhee, Jang, Cholsoon, Lee, Gina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353476/
https://www.ncbi.nlm.nih.gov/pubmed/34401789
http://dx.doi.org/10.1016/j.xpro.2021.100724