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Quantitative analysis of m(6)A RNA modification by LC-MS
N(6)-adenosine methylation (m(6)A) of messenger RNA (mRNA) plays key regulatory roles in gene expression. Accurate measurement of m(6)A levels is thus critical to understand its dynamic changes in various biological settings. Here, we provide a protocol to quantitate the levels of adenosine and m(6)...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353476/ https://www.ncbi.nlm.nih.gov/pubmed/34401789 http://dx.doi.org/10.1016/j.xpro.2021.100724 |