Rac-dependent feedforward autoactivation of NOX2 leads to oxidative burst

NADPH oxidase 2 (NOX2) produces the superoxide anion radical (O(2)(−)), which has functions in both cell signaling and immune defense. NOX2 is a multimeric-protein complex consisting of several protein subunits including the GTPase Rac. NOX2 uniquely facilitates an oxidative burst, which is describe...

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Detalles Bibliográficos
Autores principales: Hoang, Hanh My, Johnson, Hope Elizabeth, Heo, Jongyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353492/
https://www.ncbi.nlm.nih.gov/pubmed/34293347
http://dx.doi.org/10.1016/j.jbc.2021.100982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353492/
https://www.ncbi.nlm.nih.gov/pubmed/34293347
http://dx.doi.org/10.1016/j.jbc.2021.100982

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