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Rac-dependent feedforward autoactivation of NOX2 leads to oxidative burst
NADPH oxidase 2 (NOX2) produces the superoxide anion radical (O(2)(−)), which has functions in both cell signaling and immune defense. NOX2 is a multimeric-protein complex consisting of several protein subunits including the GTPase Rac. NOX2 uniquely facilitates an oxidative burst, which is describe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353492/ https://www.ncbi.nlm.nih.gov/pubmed/34293347 http://dx.doi.org/10.1016/j.jbc.2021.100982 |