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A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition

Endothelial-to-mesenchymal transition (EndMT) is the biological process through which endothelial cells transdifferentiate into mesenchymal cells. During embryo development, EndMT regulates endocardial cushion formation via TGFβ/BMP signaling. In adults, EndMT is mainly activated during pathological...

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Detalles Bibliográficos
Autores principales: Savorani, Cecilia, Malinverno, Matteo, Seccia, Roberta, Maderna, Claudio, Giannotta, Monica, Terreran, Linda, Mastrapasqua, Eleonora, Campaner, Stefano, Dejana, Elisabetta, Giampietro, Costanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353525/
https://www.ncbi.nlm.nih.gov/pubmed/34338295
http://dx.doi.org/10.1242/jcs.251371