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The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription

Gene expression involves regulation of chromatin structure and transcription, as well as processing of the transcribed mRNA. While there are feedback mechanisms, it is not clear whether these include crosstalk between chromatin architecture and mRNA decay. To address this, we performed a genome-wide...

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Detalles Bibliográficos
Autores principales: Kochan, David Z., Mawer, Julia S. P., Massen, Jennifer, Tishinov, Kiril, Parekh, Swati, Graef, Martin, Spang, Anne, Tessarz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353526/
https://www.ncbi.nlm.nih.gov/pubmed/34350963
http://dx.doi.org/10.1242/jcs.259051