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Detection of Leptomeningeal Disease Using Cell-Free DNA From Cerebrospinal Fluid

IMPORTANCE: Leptomeningeal disease (LMD) is a devastating complication of cancer that is frequently underdiagnosed owing to the low sensitivity of cerebrospinal fluid (CSF) cytologic assessment, the current benchmark diagnostic method. Improving diagnostic sensitivity may lead to improved treatment...

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Detalles Bibliográficos
Autores principales: White, Michael D., Klein, Robert H., Shaw, Brian, Kim, Albert, Subramanian, Megha, Mora, Joana L., Giobbie-Hurder, Anita, Nagabhushan, Deepika, Jain, Aarushi, Singh, Mohini, Kuter, Benjamin M., Nayyar, Naema, Bertalan, Mia S., Stocking, Jackson H., Markson, Samuel C., Lastrapes, Matthew, Alvarez-Breckenridge, Christopher, Cahill, Daniel P., Gydush, Gregory, Rhoades, Justin, Rotem, Denisse, Adalsteinsson, Viktor A., Mahar, Maura, Kaplan, Alexander, Oh, Kevin, Sullivan, Ryan J., Gerstner, Elizabeth, Carter, Scott L., Brastianos, Priscilla K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353541/
https://www.ncbi.nlm.nih.gov/pubmed/34369989
http://dx.doi.org/10.1001/jamanetworkopen.2021.20040