Cargando…

Dexmedetomidine alleviates inflammation in neuropathic pain by suppressing NLRP3 via Nrf2 activation

The aim of the present study was to investigate the mechanism by which dexmedetomidine (DEX) alleviates neuropathic pain in a chronic constriction injury (CCI) model in rats. A CCI rat model was established through sciatic nerve ligation. CCI rats were treated with DEX, the nuclear factor erythroid...

Descripción completa

Detalles Bibliográficos
Autores principales: Shan, Wenyan, Liao, Xiaoyun, Tang, Yixun, Liu, Jitong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353619/
https://www.ncbi.nlm.nih.gov/pubmed/34434260
http://dx.doi.org/10.3892/etm.2021.10479