Enantioselective α-Chlorination Reactions of in Situ Generated C1 Ammonium Enolates under Base-Free Conditions

[Image: see text] The asymmetric α-chlorination of activated aryl acetic acid esters can be carried out with high levels of enantioselectivities utilizing commercially available isothiourea catalysts under base-free conditions. The reaction, which proceeds via the in situ formation of chiral C1 ammo...

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Detalles Bibliográficos
Autores principales: Stockhammer, Lotte, Weinzierl, David, Bögl, Thomas, Waser, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353620/
https://www.ncbi.nlm.nih.gov/pubmed/34319102
http://dx.doi.org/10.1021/acs.orglett.1c02256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353620/
https://www.ncbi.nlm.nih.gov/pubmed/34319102
http://dx.doi.org/10.1021/acs.orglett.1c02256

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