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IKKε knockout alleviates angiotensin II-induced apoptosis and excessive autophagy in vascular smooth muscle cells by regulating the ERK1/2 pathway

Inhibitor of nuclear factor-κB kinase subunit ε (IKKε) is an important signal regulator in the formation of abdominal aortic aneurysm (AAA). However, the underlying mechanism remains to be elucidated. Therefore, the present study aimed to investigate the mechanism underlying IKKε function in AAA for...

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Detalles Bibliográficos
Autores principales: Chen, Ganyi, Xu, Yueyue, Yao, Yiwei, Cao, Yide, Liu, Yafeng, Chai, Hao, Chen, Wen, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353624/
https://www.ncbi.nlm.nih.gov/pubmed/34434265
http://dx.doi.org/10.3892/etm.2021.10485