Recombinant annexin A2 inhibits peripheral leukocyte activation and brain infiltration after traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) is a significant cause of death and disability worldwide. The TLR4-NFκB signaling cascade is the critical pro-inflammatory activation pathway of leukocytes after TBI, and modulating this signaling cascade may be an effective therapeutic target for treating TB...

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Detalles Bibliográficos
Autores principales: Liu, Ning, Han, Jinrui, Li, Yadan, Jiang, Yinghua, Shi, Samuel X., Lok, Josephine, Whalen, Michael, Dumont, Aaron S., Wang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353736/
https://www.ncbi.nlm.nih.gov/pubmed/34372870
http://dx.doi.org/10.1186/s12974-021-02219-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353736/
https://www.ncbi.nlm.nih.gov/pubmed/34372870
http://dx.doi.org/10.1186/s12974-021-02219-7

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