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Heterologous expression of nattokinase from B. subtilis natto using Pichia pastoris GS115 and assessment of its thrombolytic activity

BACKGROUND: Nattokinase is a fibrinolytic enzyme that has huge market value as a nutritional supplement for health promotion. In order to increase nattokinase yields, fermentation conditions, strains, cultivation media, and feeding strategies have been optimized. Nattokinase has been expressed using...

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Detalles Bibliográficos
Autores principales: Guangbo, Yan, Min, Shu, Wei, Shen, Lixin, Ma, Chao, Zhai, Yaping, Wang, Zunxi, Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353737/
https://www.ncbi.nlm.nih.gov/pubmed/34372833
http://dx.doi.org/10.1186/s12896-021-00708-4