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[6]-Paradol suppresses proliferation and metastases of pancreatic cancer by decreasing EGFR and inactivating PI3K/AKT signaling

BACKGROUND: The underlying mechanism behind the tumorigenesis and progression of pancreatic cancer is not clear, and treatment failure is generally caused by early metastasis, recurrence, drug resistance and vascular invasion. Exploring novel therapeutic regimens is necessary to overcome drug resist...

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Detalles Bibliográficos
Autores principales: Jiang, Xueyi, Wang, Jie, Chen, Peng, He, Zhiwei, Xu, Jian, Chen, Yankun, Liu, Xinyuan, Jiang, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353760/
https://www.ncbi.nlm.nih.gov/pubmed/34376189
http://dx.doi.org/10.1186/s12935-021-02118-0