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Increasing toll-like receptor 2 on astrocytes induced by Schwann cell-derived exosomes promotes recovery by inhibiting CSPGs deposition after spinal cord injury

BACKGROUND: Traumatic spinal cord injury (SCI) is a severely disabling disease that leads to loss of sensation, motor, and autonomic function. As exosomes have great potential in diagnosis, prognosis, and treatment of SCI because of their ability to easily cross the blood–brain barrier, the function...

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Detalles Bibliográficos
Autores principales: Pan, Dayu, Li, Yongjin, Yang, Fuhan, Lv, Zenghui, Zhu, Shibo, Shao, Yixin, Huang, Ying, Ning, Guangzhi, Feng, Shiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353762/
https://www.ncbi.nlm.nih.gov/pubmed/34372877
http://dx.doi.org/10.1186/s12974-021-02215-x