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Heparin-binding growth factor (HDGF) drives radioresistance in breast cancer by activating the STAT3 signaling pathway

Although reports implicate radioresistance as an important obstacle for the management of breast cancer, its molecular mechanism is elusive. Herein, we found that high HDGF levels are expressed significantly in breast cancer and exhibit a positive association with poor survival prognosis. Heparin-bi...

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Detalles Bibliográficos
Autores principales: Qiu, Lingyun, Ma, Yan, Chen, Xiaohua, Zhou, Liheng, Zhang, Haibo, Zhong, Guansheng, Zhang, Lei, Tang, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353798/
https://www.ncbi.nlm.nih.gov/pubmed/34376200
http://dx.doi.org/10.1186/s12967-021-03021-y