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High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease

BACKGROUND: Diabetes has been recognized as a risk factor contributing to the incidence and progression of Parkinson’s disease (PD). Although several hypotheses suggest a number of different mechanisms underlying the aggravation of PD caused by diabetes, less attention has been paid to the fact that...

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Detalles Bibliográficos
Autores principales: Elabi, Osama F., Cunha, João Paulo M. C. M., Gaceb, Abderahim, Fex, Malin, Paul, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353816/
https://www.ncbi.nlm.nih.gov/pubmed/34376193
http://dx.doi.org/10.1186/s12974-021-02218-8