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High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease
BACKGROUND: Diabetes has been recognized as a risk factor contributing to the incidence and progression of Parkinson’s disease (PD). Although several hypotheses suggest a number of different mechanisms underlying the aggravation of PD caused by diabetes, less attention has been paid to the fact that...
Autores principales: | Elabi, Osama F., Cunha, João Paulo M. C. M., Gaceb, Abderahim, Fex, Malin, Paul, Gesine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353816/ https://www.ncbi.nlm.nih.gov/pubmed/34376193 http://dx.doi.org/10.1186/s12974-021-02218-8 |
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