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ELK4 promotes the development of gastric cancer by inducing M2 polarization of macrophages through regulation of the KDM5A-PJA2-KSR1 axis

BACKGROUND: We tried to elaborate the molecular mechanism of ETS-like transcription factor 4 (ELK4) affecting gastric cancer (GC) progression through M2 polarization of macrophages mediated by lysine-specific demethylase 5A (KDM5A)-Praja2 (PJA2)-kinase suppressor of ras 1 (KSR1) axis. METHODS: GC ex...

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Detalles Bibliográficos
Autores principales: Zheng, Lei, Xu, Hongmei, Di, Ya, Chen, Lanlan, Liu, Jiao, Kang, Liying, Gao, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353876/
https://www.ncbi.nlm.nih.gov/pubmed/34372882
http://dx.doi.org/10.1186/s12967-021-02915-1