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Generation of combined hepatocellular‐cholangiocarcinoma through transdifferentiation and dedifferentiation in p53‐knockout mice

The two principal histological types of primary liver cancers, hepatocellular carcinoma (HCC) and cholangiocarcinoma, can coexist within a tumor, comprising combined hepatocellular‐cholangiocarcinoma (cHCC‐CCA). Although the possible involvement of liver stem/progenitor cells has been proposed for t...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Xin, Bing, Yamamoto, Masahiro, Goto, Masanori, Ooshio, Takako, Kamikokura, Yuki, Tanaka, Hiroki, Meng, Lingtong, Okada, Yoko, Mizukami, Yusuke, Nishikawa, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353893/
https://www.ncbi.nlm.nih.gov/pubmed/34051011
http://dx.doi.org/10.1111/cas.14996