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Clinical significance of signal regulatory protein alpha (SIRPα) expression in esophageal squamous cell carcinoma

Signal regulatory protein alpha (SIRPα) is a type I transmembrane protein that inhibits macrophage phagocytosis of tumor cells upon interaction with CD47, and the CD47‐SIRPα pathway acts as an immune checkpoint factor in cancers. This study aims to clarify the clinical significance of SIRPα expressi...

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Detalles Bibliográficos
Autores principales: Koga, Naomichi, Hu, Qingjiang, Sakai, Akihiro, Takada, Kazuki, Nakanishi, Ryota, Hisamatsu, Yuichi, Ando, Koji, Kimura, Yasue, Oki, Eiji, Oda, Yoshinao, Mori, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353899/
https://www.ncbi.nlm.nih.gov/pubmed/34009732
http://dx.doi.org/10.1111/cas.14971