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Adoptive cell therapy using tumor‐infiltrating lymphocytes for melanoma refractory to immune‐checkpoint inhibitors

To evaluate the feasibility of adoptive cell therapy (ACT) using ex vivo‐expanded tumor‐infiltrating lymphocytes (TILs) in Japanese patients with melanoma who failed immune‐checkpoint inhibitor therapy, an open‐label, single‐arm, pilot study was conducted. We investigated the immunological and genet...

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Detalles Bibliográficos
Autores principales: Hirai, Ikuko, Funakoshi, Takeru, Kamijuku, Hajime, Fukuda, Keitaro, Mori, Mariko, Sakurai, Masatoshi, Koda, Yuya, Kato, Jun, Mori, Takehiko, Watanabe, Naohide, Noji, Shinobu, Yaguchi, Tomonori, Iwata, Takashi, Ohta, Shigeki, Fujita, Tomonobu, Tanosaki, Ryuji, Handa, Makoto, Okamoto, Shinichiro, Amagai, Masayuki, Kawakami, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353905/
https://www.ncbi.nlm.nih.gov/pubmed/34101300
http://dx.doi.org/10.1111/cas.15009