Azithromycin enhances the cytotoxicity of DNA‐damaging drugs via lysosomal membrane permeabilization in lung cancer cells

Cancer cells use autophagy for growth, survival, and cytoprotection from chemotherapy. Therefore, autophagy inhibitors appear to be good candidates for cancer treatment. Our group previously reported that macrolide antibiotics, especially azithromycin (AZM), have potent autophagy inhibitory effects,...

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Detalles Bibliográficos
Autores principales: Toriyama, Kazutoshi, Takano, Naoharu, Kokuba, Hiroko, Kazama, Hiromi, Moriya, Shota, Hiramoto, Masaki, Abe, Shinji, Miyazawa, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353917/
https://www.ncbi.nlm.nih.gov/pubmed/34051014
http://dx.doi.org/10.1111/cas.14992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353917/
https://www.ncbi.nlm.nih.gov/pubmed/34051014
http://dx.doi.org/10.1111/cas.14992

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