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Epigenetic regulation in medulloblastoma pathogenesis revealed by genetically engineered mouse models

Medulloblastoma is the most common malignant cerebellar tumor in children. Recent technological advances in multilayered ’omics data analysis have revealed 4 molecular subgroups of medulloblastoma (Wingless/int, Sonic hedgehog, Group3, and Group4). (Epi)genomic and transcriptomic profiling on human...

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Detalles Bibliográficos
Autores principales: Shiraishi, Ryo, Kawauchi, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353939/
https://www.ncbi.nlm.nih.gov/pubmed/34050694
http://dx.doi.org/10.1111/cas.14990