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Barriers to antibody therapy in solid tumors, and their solutions

Antibody drugs have become the mainstream of cancer treatment due to advances in cancer biology and Ab engineering. However, several barriers to Ab therapy have also been identified. These include various mechanisms for Ab drug resistance, such as heterogeneity of antigen expression in tumor cells a...

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Detalles Bibliográficos
Autor principal: Matsumura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353947/
https://www.ncbi.nlm.nih.gov/pubmed/34032331
http://dx.doi.org/10.1111/cas.14983