The SARS-CoV-2 Programmed −1 Ribosomal Frameshifting Element Crystal Structure Solved to 2.09 Å Using Chaperone-Assisted RNA Crystallography

[Image: see text] The programmed −1 ribosomal frameshifting element (PFSE) of SARS-CoV-2 is a well conserved structured RNA found in all coronaviruses’ genomes. By adopting a pseudoknot structure in the presence of the ribosome, the PFSE promotes a ribosomal frameshifting event near the stop codon o...

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Detalles Bibliográficos
Autores principales: Roman, Christina, Lewicka, Anna, Koirala, Deepak, Li, Nan-Sheng, Piccirilli, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353986/
https://www.ncbi.nlm.nih.gov/pubmed/34328734
http://dx.doi.org/10.1021/acschembio.1c00324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353986/
https://www.ncbi.nlm.nih.gov/pubmed/34328734
http://dx.doi.org/10.1021/acschembio.1c00324

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