Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike Protein

[Image: see text] The SARS-CoV-2 viral spike protein S receptor-binding domain (S-RBD) binds ACE2 on host cells to initiate molecular events, resulting in intracellular release of the viral genome. Therefore, antagonists of this interaction could allow a modality for therapeutic intervention. Peptid...

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Detalles Bibliográficos
Autores principales: Sadremomtaz, Afsaneh, Al-Dahmani, Zayana M., Ruiz-Moreno, Angel J., Monti, Alessandra, Wang, Chao, Azad, Taha, Bell, John C., Doti, Nunzianna, Velasco-Velázquez, Marco A., de Jong, Debora, de Jonge, Jørgen, Smit, Jolanda, Dömling, Alexander, van Goor, Harry, Groves, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353989/
https://www.ncbi.nlm.nih.gov/pubmed/34328726
http://dx.doi.org/10.1021/acs.jmedchem.1c00477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353989/
https://www.ncbi.nlm.nih.gov/pubmed/34328726
http://dx.doi.org/10.1021/acs.jmedchem.1c00477

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