Low-dose metformin treatment in the subacute phase improves the locomotor function of a mouse model of spinal cord injury

Metformin, a first-line drug for type-2 diabetes, has been shown to improve locomotor recovery after spinal cord injury. However, there are studies reporting no beneficial effect. Recently, we found that high dose of metformin (200 mg/kg, intraperitoneal) and acute phase administration (immediately...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Wen-Ye, Ding, Han, Dunn, Tiffany, Gao, Jun-Ling, Labastida, Javier Allende, Schlagal, Caitlin, Ning, Guang-Zhi, Feng, Shi-Qing, Wu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354108/
https://www.ncbi.nlm.nih.gov/pubmed/33818507
http://dx.doi.org/10.4103/1673-5374.310695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354108/
https://www.ncbi.nlm.nih.gov/pubmed/33818507
http://dx.doi.org/10.4103/1673-5374.310695

Ejemplares similares