Transcriptome Analysis of CCR9+ T Helper Cells From Primary Sjögren’s Syndrome Patients Identifies CCL5 as a Novel Effector Molecule

INTRODUCTION: CCR9+ Tfh-like pathogenic T helper (Th) cells are elevated in patients with primary Sjögren’s syndrome (pSS) and indicated to play a role in pSS immunopathology. Here we delineate the CCR9+ Th cell-specific transcriptome to study the molecular dysregulation of these cells in pSS patien...

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Detalles Bibliográficos
Autores principales: Hinrichs, Anneline C., Blokland, Sofie L. M., Lopes, Ana P., Wichers, Catharina G. K., Kruize, Aike A., Pandit, Aridaman, Radstake, Timothy R. D. J., van Roon, Joel A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354142/
https://www.ncbi.nlm.nih.gov/pubmed/34386009
http://dx.doi.org/10.3389/fimmu.2021.702733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354142/
https://www.ncbi.nlm.nih.gov/pubmed/34386009
http://dx.doi.org/10.3389/fimmu.2021.702733

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