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Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer

Epidermal growth factor receptor (EGFR) signalling and the interleukin-6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) are aberrantly activated in ovarian cancer. However, inhibition of EGFR signalling in ovarian cancer patients resulted in a disappointing clinical benefit. In th...

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Detalles Bibliográficos
Autores principales: Yan, Meina, Han, Mutian, Yang, Xinxin, Shen, Rong, Wang, Hui, Zhang, Lubin, Xia, Sheng, Yang, Peifang, Zhai, Guanghua, Shao, Qixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354159/
https://www.ncbi.nlm.nih.gov/pubmed/34369236
http://dx.doi.org/10.1080/14756366.2021.1963240