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Downregulation of miR-142a Contributes to the Enhanced Anti-Apoptotic Ability of Murine Chronic Myelogenous Leukemia Cells

BACKGROUND: Leukemic stem cell (LSC) is thought to be responsible for chronic myelogenous leukemia (CML) initiation and relapse. However, the inherent regulation of LSCs remains largely obscure. Herein, we integratedly analyzed miRNA and gene expression alterations in bone marrow (BM) Lin(-)Sca1(+)c...

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Detalles Bibliográficos
Autores principales: Chen, Zhiwei, Xie, Yinyin, Liu, Dan, Liu, Ping, Li, Fei, Zhang, Zhanglin, Zhang, Mengmeng, Wang, Xiaolin, Zhang, Yuanliang, Sun, Xiaojian, Huang, Qiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354203/
https://www.ncbi.nlm.nih.gov/pubmed/34386429
http://dx.doi.org/10.3389/fonc.2021.718731