Downregulated lncRNA GAS5 and Upregulated miR-21 Lead to Epithelial–Mesenchymal Transition and Lung Metastasis of Osteosarcomas

Lung is the primary site of osteosarcoma metastasis, but the underlying genetic or epigenetic factors determining lung metastasis of osteosarcoma are unknown. In this study, we report the status of growth arrest specific 5 (GAS5) in lung metastatic osteosarcomas. GAS5 was generally downregulated in...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Ren, Xue, Yuan, Ye, Yuan, Bao-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354213/
https://www.ncbi.nlm.nih.gov/pubmed/34386496
http://dx.doi.org/10.3389/fcell.2021.707693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354213/
https://www.ncbi.nlm.nih.gov/pubmed/34386496
http://dx.doi.org/10.3389/fcell.2021.707693

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